1. He's Going to Die in a Few Days
2. He May Actually be Dead Already
Look at the guy above. That is not what living people look like. So if that's just a corpse the Today Show and friends have been trotting out there, we'll all feel terrible when we realize that this whole time we've been mocking a dead body. Real life isn't Weekend at Bernie's, no matter how much we want it to be.
3. He's Obviously an Insane Person
Quick question -- Would you go visit a mental institution and then crack jokes about all the crazies in there? No, because that would be fucking weird. Assuming he does not die, there's a high probability that Sheen's going to undergo some extensive psychiatric treatment. What perfectly sane man goes around talking about the tiger blood that flows through his disease-curing brain? If you said "that doesn't exist," you'd be correct.