Meet Callie Williams. She’s an ordinary girl with an extraordinary problem: Puppetitis B, a rare disease that makes a sentient puppet grow from your hand. And there’s no cure. Meet Izzy, Callie's puppet. She’s a cute, furry sociopath with a lusty carnal appetite, a brilliant mind for business, and a passion for making people unhappy … especially Callie. Yet, deep down, is Izzy truly friend or foe? Pal or parasite? And who, exactly, is doing the puppeteering in this relationship?